Mechanism of Trypanosoma cruzi Placenta Invasion and Infection: The Use of Human Chorionic Villi Explants
Congenital Chagas disease, a neglected tropical disease, endemic in Latin America, is associated with premature labor and miscarriage.During vertical transmission the parasite 2649-20 Trypanosoma cruzi (T.cruzi) crosses the placental barrier.However, the exact mechanism of the placental infection remains unclear.We review the congenital transmissio